05/17/2012, The Cochrane Library, Not only is it safe for people with asthma to exercise, but doing so could reduce their risk of asthma symptoms or attacks, according to a new evidence review in The Cochrane Library. (Source: Health Behavior News Service)

Conclusion: Sugammadex 2 mg/kg and 4 mg/kg were well tolerated and effective in patients with a history of pulmonary disease. Bronchospasm is a possibility when administering sugammadex to patients with underlying pulmonary disease. (Source: Journal of Clinical Anesthesia)

AbstractAsthma phenotypes have been developed to address the complexities of the disease. However, owing to a lack of longitudinal studies, little is known about the onset as well as the stability of phenotypes. Distinguishing phenotypes with regard to the severity or duration of the disease is essential. A phenotype covers the clinically relevant properties of the disease, but does not show the direct relationship to disease etiology and pathophysiology. Different pathogenetic mechanisms might cause similar asthma symptoms and might be operant in a certain phenotype. These putative mechanisms are addressed by the term ‘endotype’. Classification of asthma based on endotypes provides advantages for epidemiological, genetic, and drug‐related studies. A successful definition of endotype…

(Source: PharmacoEconomics and Outcomes News)

(Source: CDC Preventing Chronic Disease)

Asthma rates increased by nearly 15% from 2001 to 2010; annual costs skyrocketed. Medscape Medical News (Source: Medscape Pediatrics Headlines)

Potassium ions (purple dots) move through the narrow opening of an ion channel protein (coiled structure) to produce electrical signals and enable cellular communication. A flexible segment of the protein that’s disordered–or lacks a defined structure–temporarily blocks the passage of electrical signals after one is fired by nestling into a specific binding site. Because a protein’s 3-dimensional shape determines its function, it’s intriguing that an unstructured piece of one–and potentially many others–has certain tasks, too. This ion channel work could help explain why and also lead to novel ways to treat channel-related disorders, such as epilepsy, asthma and Parkinson’s disease. Image courtesy of Yu Zhou. (Source: NIGMS Biomedical Beat)

Stray voltage, also known as stray electricity, ground current or neutral-to-earth voltage, is generally defined as a current that arises both from the distribution systems of the electrical utilities, e.g., underground wires, power lines, and from the electrical systems… (Source: NaturalNews.com)

Conclusions: The results indicate that safety profiles of high doses of BDP and FP with respect to adrenal function are similar, but FP is more efficacious than that of BDP in improving pulmonary function test. (Source: Indian Journal of Pharmacology)

Conclusions: A discrepancy between subjective assessment of asthma control and ACT score was observed in the examined group of patients. The frequency of asthma exacerbations (according to questionnaire) was describing the degree of asthma control more precisely than self-assessment. Older age and longer disease duration were combined with significantly worse asthma control. Better asthma control was combined with the presence of influenza vaccinations in medical history.
PMID: 22562271 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)

Home Air Check™ can help improve indoor air environments by identifying chemical pollutants that can trigger asthma attacks

(PRWeb May 18, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9515991.htm

The Home Medical Equipment Rentals industry has adapted to a shifting landscape during the past five years. Changes in Medicare regulation resulted in higher costs and limited revenue for operators….

(PRWeb May 18, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9521025.htm

MD247 announced the launch of its newly redesigned website at http://www.md247.com on Thursday. The modified website is intended to improve user interface, and…

(PRWeb May 17, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9519056.htm

This study investigated the effect of LPS on antigen‐stimulated mast cell degranulation and the underlying mechanisms. We found that LPS enhanced degranulation in RBL‐2H3 cells and mouse peritoneal mast cells upon FcɛRI activation, in dose and time‐dependent manners. Parallel to the alteration of degranulation, LPS increased FcɛRI‐activated Ca2+ mobilization, as well as Ca2+ entry through store‐operated calcium channel (SOC) evoked by thapsigargin (TG). Blocking Ca2+ entry through SOCs completely abolished LPS enhancement of mast cell degranulation. Consistent with functional alteration of SOCs, LPS time‐dependently increased mRNA and protein levels of Orai1 and STIM1, two major subunits of SOCs. In addition, LPS time‐dependently increased mRNA level of toll‐like receptor…

(MedPage Today) — Asthma prevalence reached its highest level ever in 2010 — 8.4% of the population, up from 7.3% in 2001, according to the CDC. (Source: MedPage Today Pediatrics)

Latest numbers from the CDC find 19 million adults and 7 million kids have the illness today (Source: The Doctors Lounge – Health News)

In conclusion, salbutamol can decrease acute and chronic inflammation, possibly through the stimulation of β-2 adrenergic receptors. This anti-inflammatory effect may be of significance in asthma treatment, where inflammation also takes part in the etiopathology. This study reveals that salbutamol has significant antioxidative effects, which at least partially explain its anti-inflammatory capabilities. These findings presented here may also shed light on the roles of β-2 adrenergic receptors in inflammatory and hyperalgesic conditions. (Source: Experimental Diabetes Research)

They reduce inflammation in the lungs, improving control of asthma symptoms (Source: The Doctors Lounge – Health News)

Conclusions: The harmonization of endpoint definitions, terminology, and clinical trial design paradigms provides consistency across clinical trial studies that can facility (sic) clinician acceptance of results and the evaluation of safety and effectiveness of devices and medicines for atrial fibrillation.” http://goo.gl/ZstA0

Harvard Medical School Q&A blog doctor reflects on his readers’ feedback

Dr. Komaroff from the blog Ask Doctor K.: “Since I began this column last September, I’ve received a lot of mail — both emails and “snail mail.” Mostly it’s been health questions. I can’t answer them all, but I try to answer as many as I can. However, I’ve also received complaints. Sometimes they represent an honest difference of perspective. On occasion, they reflect th…

Conclusions. Island Puerto Rican youth are at a health disadvantage compared with mainland youth. Public health research is needed to fully understand and combat health challenges among Puerto Rican youth. (Source: Clinical Pediatrics)

ConclusionFlexible bronchoscopy with bronchial lavage is a safe adjunctive therapy in pediatric asthmatics with respiratory failure resulting in reduced mechanical ventilation and intensive care length of stay. Restoring lung volume in certain asthmatics during respiratory failure may be deemed beneficial. Further validated studies are necessary to recommend bronchoscopy to the present, accepted treatment regimen in pediatric asthmatic respiratory failure. Pediatr Pulmonol. © 2012 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)

ConclusionFeNO is more than a marker useful for screening atopy or symptomatic bronchial inflammation and may also be a proxy for cytokine deregulation and “allergic response” phenotype possibly established in fetal period due to transplacental PAH exposure. Preliminary results of our study should encourage more studies on intrauterine PAH exposure and later respiratory symptoms. Pediatr Pulmonol. © 2012 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)

CXCL10 (IP10) is involved in mast cell migration to airway smooth muscle (ASM) bundles in asthma. We aimed to investigate the role of cytokine-induced MAPK activation in CXCL10 production by ASM cells from people with and without asthma. Confluent growth-arrested ASM cells were treated with inhibitors of the MAPKs ERK, p38, and JNK and transcription factor NF-B, or vehicle, and stimulated with IL-1β, TNF-α, or IFN-, alone or combined (cytomix). CXCL10 mRNA and protein, JNK, NF-B p65 phosphorylation, and I-Bα protein degradation were assessed using real-time PCR, ELISA, and immunoblotting, respectively. Cytomix, IL-1β, and TNF-α induced CXCL10 mRNA expression more rapidly in asthmatic than nonasthmatic ASM cells. IL-1β and/or TNF-α combined with IFN- s…

Largest Medical Equipment Supplier in Central Florida to Become In-Network Provider for BCBS

(PRWeb May 16, 2012)

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In order to protect the health of MD247 telemedicine program members, the provider of supplemental medical services has retracted a press release regarding heart attack symptoms.

(PRWeb May 16, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9513328.htm

All City Environmental is ramping up services to give families urgently needed mold removal to stop the health risks associated with mold in the home. Spring is a key time for mold to grow, causing an…

(PRWeb May 15, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9506433.htm

Alley Heating and Air Conditioning is providing speedy service for homeowners who want their air purification done right. Spring is the key time to address indoor air quality to prevent serious health…

(PRWeb May 15, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9506655.htm

LinkedIn is the place for people interested in telemedicine to visit and discuss the options that the product can bring to the medical market. Visit…

(PRWeb May 15, 2012)

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Dr. Carol Francis, in an objective attempt to understand the experiences claimed by Braco Gazing attendees, interviewed 30 Braco Gazing participants who experienced many different types of healing and…

(PRWeb May 14, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9503089.htm

CanadaDrugsOnline.com has launched a mobile version of their leading Canadian pharmacy website. Customers can now search, buy and refill their prescriptions any time, anywhere. CanadaDrugsOnline.com…

(PRWeb May 14, 2012)

Read the full story at http://www.prweb.com/releases/canadianpharmacy/mobile/prweb9500385.htm

With recent reviews indicating that Medicare will fail aging Baby Boomers, MD247 Founder Thomas Meehan rolled out the red carpet for interested parties to check out the MD247 telemedicine program.

(PRWeb May 14, 2012)

Read the full story at http://www.prweb.com/releases/2012/5/prweb9503760.htm