Asthma News

Authors: Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M
Asthma is a common, disabling inflammatory respiratory disease that has increased in frequency and severity in developed nations. We review studies of murine allergic airway disease (MAAD) and human asthma that evaluate the importance of Th2 cytokines, Th2 response-promoting cytokines, IL-17, and proinflammatory and anti-inflammatory cytokines in MAAD and human asthma. We discuss murine studies that directly stimulate airways with specific cytokines or delete, inactivate, neutralize, or block specific cytokines or their receptors, as well as controversial issues including the roles of IL-5, IL-17, and IL-13Ralpha2 in MAAD and IL-4Ralpha expression by specific cell types. Studies of human asthmatic cytokine gene an…

Random Posts

• Gene Blamed For Immunological Disorders Shown To Protect Against Breast Cancer Development
• Experimental Drug May Dampen Severe Asthma
• Asthma Control Test correlates well with the treatment decisions made by asthma specialists
• Prenatal Nutrition, Postnatal Allergy Protection
• Home and community care services: a major opportunity for preventive health care
• Lack of Association between Neuropeptide S Receptor 1 Gene (NPSR1) and Eczema in Five European Populations.
• Oral alternative to allergy shots improves hay fever (Yahoo Health)
• Stomach Reduction Surgery Via Mouth a U.S. First (Yahoo Health)